We are truly sorry to hear that you're feeling under attack and powerless. Let's bring your situation before the Lord in prayer and seek His wisdom and guidance.
Firstly, we must remember that our battle is not against flesh and blood, but against the rulers, against the authorities, against the world rulers of this darkness, against the spiritual forces of evil in the heavenly places. Therefore, take up the whole armor of God, that you may be able to withstand in the evil day, and having done all, to stand. Stand therefore, having fastened the belt of truth around your waist, and having put on the breastplate of righteousness. Stand therefore, having fastened the belt of truth around your waist, and having put on the breastplate of righteousness, and having shod your feet with the preparation of the Good News of peace; above all, taking up the shield of faith, with which you will be able to quench all the fiery darts of the evil one. And take the helmet of salvation, and the sword of the Spirit, which is the word of God; praying always with all prayer and supplication in the Spirit, and watching thereunto with all perseverance and supplication for all saints. Ephesians 6:12-18 WEB.
Let's address the issues you're facing.
In the workplace, it's important to maintain integrity and professionalism. When others speak ill of you, continue to do good and trust that the truth will come to light. In the past, Jesus advised, But I tell you, don't resist him who is evil; but whoever strikes you on your right cheek, turn to him the other also. And if any man would go to law with you and take away your coat, let him have your cloak also. And whoever compels you to go one mile, go with him two. Give to him who asks you, and don't turn away him who desires to borrow from you. You have heard that it was said, 'You shall love your neighbor, and hate your enemy.' But I tell you, love your enemies, bless those who curse you, do good to those who hate you, and pray for those who mistreat you and persecute you. Matthew 5:39-44 WEB.
We pray that God will give you wisdom and discernment in handling this situation. Expose her before His throne and ask for His Justice. It is also important to go to your boss directly, ask what the issues are and pray for his discernment. Pray for your colleague, that she may be convicted of her actions and seek forgiveness. If it is His will for you to have a different job, pray for His guidance and direction. Ask Him what steps to take and which jobs to apply for.
Regarding your marriage, we are reminded that a husband and wife are to submit to one another out of reverence for Christ. Wives, be in subjection to your own husbands, as to the Lord. For the husband is the head of the wife, as Christ also is the head of the assembly, being himself the savior of the body. But as the assembly is subject to Christ, so let the wives also be to their own husbands in everything. Husbands, love your wives, even as Christ also loved the assembly, and gave himself up for it. Ephesians 5:21-25 WEB.
It's crucial to support your husband as he battles this issue of bipolar disorder, but it's equally important to protect yourself from any harm or abuse. Seek professional help and counseling together.
We pray for your husband's healing and restoration. May God grant him deliverance from this disorder and bring peace to your marriage.
Heavenly Father, we come before You, lifting up our sister who feels powerless and under attack. We pray for Your divine intervention in her workplace, that You would expose any lies and bring the truth to light. We pray for her colleague, that she would be convicted of her actions and seek forgiveness. We also pray for her husband, that You would heal him of this bipolar disorder and bring restoration to their marriage.
We pray all these things in the powerful name of Jesus Christ, who is the only way to access God and be saved.
Lastly, we encourage you to cast all your anxieties on him, because he cares for you. Be sober and self-controlled. Be watchful. Your adversary, the devil, walks around like a roaring lion, seeking whom he may devour. Withstand him steadfast in your faith, knowing that your brothers who are in the world are undergoing the same sufferings. But may the God of all grace, who called you to his eternal glory by Christ Jesus, after you have suffered a little while, perfect, establish, strengthen, and settle you. To him be the glory and the power forever and ever. Amen. 1 Peter 5:7-11 WEB.
Prayer Focus: God, Thank You. Thank You for loving me. God, I ask You in Jesus’ name bless me with everything that I stand in need of and everything You want me to have. Bless me to know You in truth, fall in love with You with all my heart, mind, soul, body, and strength and never fall out of love with You. Bless me to have an ever growing closer stronger, more intimate relationship with You. Bless me with the love, desire, strength, and the spirit of obedience to always delight myself in You, seek first Your kingdom, and Your righteousness. Help and strengthen me God to always respect and obey You. Bless me to trust You with all my heart, acknowledge You in all my ways, and lean not to my own understanding. 
