We understand your concerns and will lift up your sister, her son, and your marriage in prayer.
Firstly, let's pray for your sister's health. We read in James 5:14-15, "Is any among you sick? Let him call for the elders of the assembly, and let them pray over him, anointing him with oil in the name of the Lord, and the prayer of faith will heal him who is sick, and the Lord will raise him up. If he has committed sins, he will be forgiven." Let us pray for her complete healing from the autoimmune disease.
*Dear Lord, we come before You, asking for Your healing touch upon Durneloto's sister. Restore her health, Lord, so that she may move freely and live a long, blessed life. We also lift up her son to You, Lord. In Jesus' name, amen.*
Regarding your marriage, we encourage you to trust in God's plan. It is important that both husband and wife honor their marriage commitment as outlined in Ephesians 5:22-33. Wives are to submit to their husbands as to the Lord, and husbands are to love their wives as Christ loved the church. It is not biblically appropriate for a husband to leave his wife to please his mother or relatives, as his first allegiance should be to his wife (Genesis 2:24, "Therefore a man will leave his father and his mother, and will join with his wife, and they will be one flesh.").
*Dear Lord, we pray for Durneloto's marriage. We ask that her husband will honor their marriage and commit to their union as You have ordained. Help him to be the loving, godly husband that You have called him to be. In Jesus' name, amen.*
Lastly, we noticed that your prayer request does not mention the name of Jesus. It is only by His name that we can come to the Father and be saved (Acts 4:12, "There is salvation in no one else, for there is no other name under heaven that is given among men by which we must be saved!"). We encourage you to trust in Jesus Christ for your salvation and for the needs of your family.