We understand your concern for your daughter-in-law Alexis and your son Jacob. Let's bring this situation before the Lord in prayer and seek His guidance and intervention.
Firstly, we must remember what the Apostle Paul says in Ephesians 4:29, "Let no corrupt speech proceed out of your mouth, but such as is good for building up as the need may be, that it may give grace to those who hear." It's important that Alexis understands the impact of her words and that communication in a marriage should be life-giving and encouraging.
Regarding her weight struggle, we pray that she finds strength and comfort in the Lord. As it is written in 1 Corinthians 6:19-20, "Or don’t you know that your body is a temple of the Holy Spirit which is in you, which you have from God? You are not your own, for you were bought with a price. Therefore glorify God in your body and in your spirit, which are God’s." May she be guided to take care of her body as a temple of the Holy Spirit.
As for the concern about how she might treat your grandchild, we pray that she will exhibit the fruits of the Spirit, which are love, joy, peace, patience, kindness, goodness, faithfulness, gentleness, and self-control (Galatians 5:22-23).
Let us pray:
"Dear Heavenly Father, we come before You today to lift up Alexis and Jacob. Lord, we ask that You help Alexis to communicate with kindness and respect, building up her husband as Your word instructs. We also ask for Your strength and guidance as she cares for her body, knowing that it is a temple of the Holy Spirit. And as she becomes a mother, help her to be patient, loving, and gentle with her child. In all things, Lord, help her to be a reflection of Your love and grace. We pray this in Jesus' name, Amen."
Lastly, we encourage you to continue praying fervently for them, as James 5:16 tells us, "The effective, earnest prayer of a righteous person has great power and produces wonderful results." Keep trusting in the Lord and His power to change hearts and situations. If you haven't already, ensure that Alexis and Jacob have a personal relationship with Jesus Christ, as it is only through Him that true transformation can occur (John 14:6).
Articles:
Let's continue to agree with Smilee in a heartfelt "Amen!" Trusting God's healing power. "For I am the Lord who heals you" (Ex. 15:26). Keep believing for complete recovery and a swift return to work. In Jesus' name! 
Smilee:
Let's lift up @Angeline's sister for divine help, @Gileanxath's brother Nithin for healing, and @Siyran for positive colonscopy results. Please join in prayer! 
**Let's Pray Together!** 
For @Anonymous' husband, that God brings him back home.
For @PrayerWarrior360's healthy pregnancy & family needs.
For strength & recovery for friends and language skills (Arabic & English).
For job blessings and family support for @Gwimsethshar.
For peace & trust in God for those struggling.
In Jesus' Name.
