We understand the deep pain and loneliness you're feeling, especially when you see your children enjoying time with their in-laws. It's commendable that you're making efforts to communicate, and our hearts go out to you during this difficult time. Remember, God cares about your pain and wants to comfort and guide you.
Firstly, let's pray together:
Dear Heavenly Father,
We come before You, lifting up this dear mother who is feeling heartbroken and forgotten. Lord, You know her pain and the depth of her love for her children. We pray, Lord Jesus, that You would heal her broken heart and fill her with Your peace. We ask that You would soften the hearts of her children and draw them back into a loving, godly relationship with their mother. Give her the strength and wisdom to reach out in love, and help her children to respond in kind. Lord, we also ask that You provide godly spouses for her children and that all marriages honor God. We ask that the goal for any boyfriend or girlfriend that they have would be to marry a Christian Believer.
In Jesus name, we ask these things.
Now, let's look at what the Bible says about relationships and communication. In Malachi 4:6, God speaks about turning the hearts of the parents to their children and the hearts of the children to their parents. This shows God's desire for reconciliation and strong family bonds. However, in the majority of scripture, the focus is on the child to obey and honor their parents. Therefore the focus of the prayer should be to change the child's heart to honor and communicate with their mother.
In addition, consider the words of Ephesians 4:32, Be kind to one another, tenderhearted, forgiving each other, just as God also in Christ forgave you. As you reach out to your children, do so with kindness, patience, and forgiveness. Remember that love covers a multitude of sins (1 Peter 4:8).
While it's important to make efforts to communicate, it's also crucial to set boundaries and respect their lives. Perhaps they are busy and struggling with their own challenges. Be patient and continue to pray for them.
Lastly, remember that God is your ultimate comfort and strength. Turn to Him in your loneliness, and He will sustain you. As it says in Psalm 34:18, Yahweh is near to those who have a broken heart, and saves those who have a crushed spirit. Another important scripture to remember is Psalm 68:5, A father of the fatherless, and a defender of the widows, is God in his holy habitation. Our Heavenly Father will be your comfort and help in this time of need.
Regarding your mention of divorce, we want to remind you that God's original plan for marriage is a lifelong commitment between a man and a woman. While we understand that life doesn't always go as planned, we encourage you to seek God's will for any future relationships, keeping in mind the sanctity of marriage. We are praying for godly spouses and marriages that honor God. We will encourage individuals to pursue relationships that align with biblical principles.
We noticed that you did not mention the name of Jesus Christ, Jesus, or Christ in your prayer. Please remember that salvation comes only through believing in Jesus Christ. As it says in Acts 4:12, There is salvation in none other, for neither is there any other name under heaven, that is given among men, by which we must be saved. And also in John 14:6, Jesus said to him, I am the way, the truth, and the life. No one comes to the Father, except through me. We encourage you to put your faith and trust in Jesus Christ to intercede for you and work in your life for the best.
Prayer Focus: God, Thank You. Thank You for loving me. God, I ask You in Jesus’ name bless me with everything that I stand in need of and everything You want me to have. Bless me to know You in truth, fall in love with You with all my heart, mind, soul, body, and strength and never fall out of love with You. Bless me to have an ever growing closer stronger, more intimate relationship with You. Bless me with the love, desire, strength, and the spirit of obedience to always delight myself in You, seek first Your kingdom, and Your righteousness. Help and strengthen me God to always respect and obey You. Bless me to trust You with all my heart, acknowledge You in all my ways, and lean not to my own understanding. 
