We understand that you are going through a tremendously challenging time with your husband's health and emotional struggles. Firstly, we commend you for your unwavering faith and dedication to prayer, and submitting your request in Jesus's name. It is only through the name of Jesus that we have access to the Father and it is only through Jesus that anyone can be saved. It is so important to pray in Jesus's name and encourage everyone to only pray this way as it is the only way according to the Bible. Let's turn to the Word of God for guidance and encouragement.
In times of difficulty, we remember that God is close to the brokenhearted and saves those who are crushed in spirit.
Psalm 34:18 WEB: Yahweh is near to those who have a broken heart, and saves those who have a crushed spirit.
We need to pray for your husband's healing, recognizing that God's will is perfect and that He desires wholeness for all of us.
3 John 1:2 WEB: Beloved, I pray that you may prosper in all things and be healthy, even as your soul prospers.
However, it's crucial to address the spiritual aspect as well. Your husband's anger, depression, and refusal to take his medication or cooperate with treatment highlight a deeper spiritual battle. We must pray for his spiritual renewal and surrender to God's will.
Ephesians 4:26-27 WEB: Be angry, and don't sin. Don't let the sun go down on your wrath, neither give place to the devil.
We also encourage you to continue in fervent prayer and unyielding faith. God hears your prayers and knows the depth of your concern.
James 5:16 WEB: Confess your offenses to one another, and pray for one another, that you may be healed. The insistent prayer of a righteous person is powerfully effective.
As for your husband's reluctance to seek help or take his medication, we must pray for a change of heart and a willingness to cooperate with the healing process.
Philippians 2:13 WEB: for it is God who works in you both to will and to work, for his good pleasure.
Lastly, we want to address the importance of continuing in love and patience, even in the face of extreme frustration. God calls us to love one another as He has loved us, and this includes extending grace and patience to your husband.
Ephesians 4:2 WEB: with all humility and gentleness, with patience, bearing with one another in love;
Let us pray together:
Heavenly Father, we come before You in the name of Jesus, lifting up our sister and her husband. Lord, You know the depth of their struggles and the heaviness of their burdens. We ask for Your healing touch upon her husband, physically, emotionally, and spiritually. Restore his faith, Lord, and draw him back to You. Give him a willing spirit to cooperate with treatment and a heart that yearns for Your presence.
Father, we also pray for our sister. Strengthen her faith, Lord, and fill her with Your peace that surpasses all understanding. Give her the patience and grace to continue loving and supporting her husband, even in the face of frustration.
In the name of Jesus, we rebuke the spirits of anger, depression, and hopelessness that have taken hold of her husband. We declare Your healing and restoration over their lives, and we ask that Your will be done.
Thank You, Lord, for hearing our prayers. In Jesus' name, we pray. Amen.
Continue to stand strong in your faith, trusting that God is at work in your situation. Keep praying and seeking God's will, and remember that He is always with you, even in the darkest of times and never forget to keep praying in Jesus's name.
Welcome! "Therefore welcome one another as Christ has welcomed you, for the glory of God" (Rom 15:7). Trust that God has a purpose for your presence here. Let's stand united in prayer, believing for breakthroughs! 
