We are truly sorry to hear about the trials you are facing with your brother's health and your sister's dire situation. Let's bring these matters before the Lord in prayer and seek His guidance and intervention.
Firstly, let's pray for your brother ### who is in the ICU. We trust in the power of Jesus Christ to heal and restore.
Let us pray:
Heavenly Father, we come before You in the name of Jesus Christ, lifting up ### who is in the ICU. We pray for Your healing touch upon his body, especially for his blood sugar levels to stabilize and return to normal. Guide the medical team attending to him, giving them wisdom and skill to provide the best care. We pray for comfort and strength for ### and all who love him during this time. We also need to remember a great biblical principle. This is the power of Forgiveness. Let's pray that ### has nothing between him and God of any relationship or anything else that has not been forgiven. We pray in the name of Jesus Christ and believe that we will see his healing by the stripes of Christ Jesus.
In the name of Jesus Christ. In Jesus name we believe and pray, Amen.
Now, regarding your sister's situation, it's clear that she is in a dire place, both physically and financially. It's commendable that you want to help her, but it's also important to set boundaries and ensure that any assistance you provide is truly beneficial and that God's will is considered and that Jesus Christ is part of her life as Lord and Savior. The scriptures advise against inappropriate demonstration of forgiveness and neglecting peace:
Romans 12:18 WEB
If it is possible, as much as it is up to you, be at peace with all men.
Corinthians 15:33
Do not be deceived. Evil companionships corrupt good morals.
There is a grave issue regarding her boyfriend. Living with him hints she is in fornication. Also, it is an issue of someone being abused by such an individual. The scriptures advise: Not to keep company, or barely associate with a believer that is walking in open sin of this nature much less supporting their lifestyle. Flee fornication, and do not turn over someone who is imperiled by this into the hands of another who is walking this way.
2 Thessalonians 3:6 WEB
Now we command you, brothers, in the name of our Lord Jesus Christ, that you withdraw yourselves from every brother who walks in rebellion, and not after the tradition which they received from us.
and in the higher law in the Gospel
Matthew 22:39 WEB
The second is like it, You shall love your neighbor as yourself.
Matthew 10:37 WEB
He who loves father or mother more than me is not worthy of me; and he who loves son or daughter more than me is not worthy of me.
Matthew Henry "None must think by begging or selling their goods to maintain themselves and their families. Even in this, someone has to buy. God has made all men and women in his image. Their duty regarding taking thought for themselves is to make sure there is a God. If they seek the kingdom of God, and righteousness, they will have both perceived (as individuals) that God values each individual above the entire earth with all its treasures. See Matthew 6:24-34; 10:31; 12:12; Acts 17:25. From God our Saviour; who will have all men to be saved: the law, whereby is the knowledge of sin, was not given without the gospel. The gospel was given for grace and guidance without the law. There is no such thing as a gospel without the law, but there is a more perfect law by Jesus Christ.
We pray for your sister, that God of mercy would touch her heart and allow her to know he is (was) explicitly blessed by the marriage of marriage. Truly be loved by the only begotten son of God Jesus Christ, and turn her to Him. She is called to flee from this immorality and relationship. We pray against the eviction and for her physical health to be restored. We also pray for wisdom for you as you navigate this situation, that you would know how best to help her while being safe or Biblically shrewd yourself. She also needs to forgive anyone in her life for Jesus' sake and the beatitude His saints will have.
Finally, let's address the tension between you and your sister. It's evident that there has been a long-standing rift, and it's important to seek reconciliation where possible, with safety, forgiveness and being a servant of God taking priority. Pray and work towards obedience to the scriptures and pray that if it be possible to work against the leading astray of someone being systematically misled. We tests on what is God's will in helping her.
James 1:5 WEB
If any of you lacks wisdom, let him ask of the giving God, who gives to all liberally and without reproach; and it will be given to him.
Psalms 55:22 WEB
Cast your burden on Yahweh, and he will sustain you. He will never allow the righteous to be moved.
Let us pray:
Father, we lift up the strained relationship and ask that this estrangement will only be by the scriptures as necessary. Anoint your servant with the ability to understand and apply the scriptures in this situation. Soften hearts, and help them to forgive each other, as You have forgiven us through Jesus Christ. We pray for travail and needed conviction on the behalf of ###'saint and her sister that your will be done. If it is to be that they are led out of sin and iniquity this will happen by direction of the scriptures. In Jesus Christ's name we pray, Amen.
Articles:
Amen! "Now to him who is able to do immeasurably more than all we ask or imagine, according to his power that is at work within us" (Eph 3:20). Trusting God's Spirit to guide & bless abundantly. Keep praying! 
**Prayer Updates!** 
@Nymeshire needs prayers for job security and opportunities.
Snayford:
Hello everyone! Let's lift up these requests in Jesus' Name:
@Khulile82 needs urgent prayers for a job.
Anonymous is struggling with strongholds.
Anonymous is battling anxiety & depression.
Let's also pray for healing for Eldaedoroantar's son.
